Mounjaro works by suppressing appetite and making you feel fuller for a longer time (Pic: Instagram/X)
Hansal Mehta says he lost ten kilograms after using Mounjaro – a prescription medicine used to improve blood sugar control in adults with type 2 diabetes and support weight management in those with obesity. The 57-year-old filmmaker, on a social media post, opened up on his pre-diabetes and increasing weight and paired the drug with major lifestyle changes.
“Under medical guidance, I began Mounjaro to address rising blood sugar levels in the pre-diabetic range and to manage my steadily increasing weight. Paired with a committed lifestyle shift — high-protein meals, minimal sugar and alcohol, regular strength training, proper hydration, 14–18-hour intermittent fasting, NMN + Resveratrol supplements, and better sleep —I’ve seen tangible results,” Mehta wrote on X.
“In just a few months, I’m down nearly 10 kilos. My muscle mass has significantly improved, my energy levels are higher, and my blood sugar readings are now well within the normal range. Insulin resistance has dropped, and yes, the old clothes are falling off!”
Mehta said he was sharing his experience with Mounjaro – which mimics natural hormones to enhance insulin secretion and regulate appetite—to address the stigma around the medication.
“There’s no shame in taking charge of your health with the tools available to you—especially when done responsibly and under supervision. If you’re struggling with similar issues, speak to your healthcare provider. It might just be the beginning of a journey you’ll be grateful for,” he continued.
What is Mounjaro?
Mounjaro 2.5mg solution for injection is administered once weekly subcutaneously in the abdomen, thigh, or upper arm. To maximise its benefits, doctors advise maintaining a consistent injection schedule and complementing treatment with a healthy diet and regular exercise.
How does Mounjaro work for weight loss?
According to experts, Mounjaro works by suppressing appetite and making you feel fuller for a longer time. It changes the rate at which your stomach empties.
Being a new-class drug, Mounjaro activates two receptors, instead of being a single-receptor agonist, which semaglutides like Ozempic and Wegovy do, and that is why doctors also call it a ‘dual-agonist.’ This double agonist approach seems to cause people who use Mounjaro injections to lose even more weight than those who use a single-agonist medication.
Experts say the three receptors stimulate hormones that control blood sugar levels and reduce appetite, triggering weight loss. The receptors are known as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP).
Wegovy and Ozempic activate the GLP-1 receptor, while Mounjaro activates two receptors: both GLP-1 and GIP.
Should you be cautious?
Doctors say all weight-loss and diabetic drugs are highly effective, yet their intake needs to be monitored. Here are some reasons to be cautious about Mounjaro:
- According to experts, Mounjaro is not approved for everyone, and only those with diabetes or pre-diabetes should take it.
- Just like Ozempic and Wegovy, if you lose weight with Mounjaro, you likely will need to keep taking the medication forever to keep the weight off.
- It can cause a few unpleasant gastrointestinal side effects like nausea, diarrhoea, vomiting, constipation, abdominal pain, and indigestion.
How long do the side effects last?
Doctors say it depends on how the person’s body reacts to Mounjaro, as some of the side effects of the medicine may be temporary and last a few days or weeks. While others may last longer or require long-term treatment, especially if they are serious (see above).
To minimise your risk of side effects and help your body get used to the drug, your doctor can begin with the lowest dose and gradually increase it.
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