Two new studies presented at the Society for Cardiovascular Angiography and Interventions (SCAI) 2025 scientific sessions in Washington, DC, have sounded the alarm on the escalating cardiovascular dangers linked to tobacco and cannabis use. According to the findings, deaths from heart disease could surge by up to 50% in the next five years due to rising consumption of these substances.

One study led by researchers at Wayne State University focused on ischemic heart disease — also known as coronary heart disease — which results from narrowed or blocked coronary arteries reducing blood flow to the heart. The team analysed data spanning 1999 to 2020 involving individuals aged 25 and older. Their projections indicate a worrying 43.7% increase in tobacco-related heart disease deaths by 2030. While the data showed a decline in female mortality, it highlighted a sharp increase among men.

“Tobacco-related ischemic heart disease remains a leading cause of death and is not a thing of the past,” said Roopeessh Vempati, a lead researcher from Wayne State University. “Understanding which groups are most vulnerable is key to designing targeted public health interventions.”

Meanwhile, the second study, conducted by researchers at Sinai Hospital in the US, examined over 1.3 million patients admitted for heart failure. The findings revealed that those with cannabis use disorder (CUD) — a condition involving problematic cannabis use — were at significantly higher risk of severe cardiovascular complications. Patients with both heart failure and CUD were 50% more likely to experience a heart attack, 27% more likely to develop cardiogenic shock, and 48% more likely to suffer from arrhythmias.

Interestingly, the study also found that individuals with cannabis use disorder had a lower risk of death compared to those without the disorder. However, researchers emphasized that this does not negate the serious cardiovascular risks associated with cannabis use.

“Even if mortality is lower, the increased likelihood of heart attacks and arrhythmias among cannabis users is cause for concern,” said Dr. Syed Ishaq, Internal Medicine resident at Sinai Hospital. “Clinicians and public health professionals need to educate patients early about these risks—before they reach the stage of heart failure.”

SCAI President Dr. James B. Hermiller stressed, “Despite ongoing awareness efforts, tobacco and cannabis use remains widespread. These studies highlight the urgent need for continued vigilance and education regarding their impact on heart health.”

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